Dieter Lütjohann Selected Research

gamma-sitosterol (beta-sitosterol)

12/2021	Plant Sterol-Poor Diet Is Associated with Pro-Inflammatory Lipid Mediators in the Murine Brain.
10/2018	Comment on Tauriainen et al.: Serum, liver and bile sitosterol and sitostanol in obese patients with and without NAFLD.
5/2015	Vascular effects of oxysterols and oxyphytosterols in apoE -/- mice.
2/2013	Role of the ABCG8 19H risk allele in cholesterol absorption and gallstone disease.
6/2011	Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice.
1/2008	Moderately elevated plant sterol levels are associated with reduced cardiovascular risk--the LASA study.
4/2006	Dietary plant sterols accumulate in the brain.

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Dieter Lütjohann Research Topics

Disease

44	Alzheimer Disease (Alzheimer's Disease) 03/2021 - 02/2002
35	Atherosclerosis 01/2020 - 04/2007
28	Inflammation (Inflammations) 05/2021 - 08/2008
15	Hypercholesterolemia 09/2017 - 02/2002
14	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 09/2009
8	Coronary Artery Disease (Coronary Atherosclerosis) 11/2022 - 01/2006
7	Atherosclerotic Plaque (Atheroma) 01/2018 - 07/2010
6	Alcoholic Fatty Liver 01/2021 - 03/2010
5	Gallstones (Gallstone) 01/2022 - 12/2009
5	Non-alcoholic Fatty Liver Disease 10/2018 - 08/2008
5	Multiple Sclerosis 01/2018 - 02/2005
5	Fatty Liver 01/2017 - 11/2007
5	Sitosterolemia 01/2016 - 03/2005
4	Cerebrotendinous Xanthomatosis 01/2021 - 03/2010
4	Disease Progression 01/2021 - 09/2006
4	Cognitive Dysfunction 01/2021 - 06/2009
4	Infections 01/2019 - 09/2006
4	Fibrosis (Cirrhosis) 10/2017 - 06/2010
4	Body Weight (Weight, Body) 09/2017 - 01/2003
4	Aortic Valve Stenosis (Aortic Stenosis) 07/2015 - 04/2008
4	Cholelithiasis 06/2014 - 12/2009
4	Coronary Disease (Coronary Heart Disease) 09/2009 - 05/2007
3	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 03/2022 - 11/2007
3	Hypertension (High Blood Pressure) 01/2022 - 07/2008
3	Obesity 12/2021 - 03/2006
3	Neoplasms (Cancer) 01/2021 - 12/2009
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 07/2006
3	Type 2 Diabetes Mellitus (MODY) 01/2020 - 03/2006
3	Neuroblastoma 01/2010 - 04/2006
2	Atrophy 01/2021 - 06/2009
2	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 01/2020 - 01/2017
2	Metabolic Diseases (Metabolic Disease) 01/2020 - 09/2015
2	Astrocytoma (Pilocytic Astrocytoma) 12/2016 - 04/2006
2	Asthma (Bronchial Asthma) 02/2016 - 01/2012
2	Hepatomegaly 01/2016 - 08/2015
2	Necrosis 01/2016 - 01/2011
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2015 - 08/2015

Drug/Important Bio-Agent (IBA)

98	CholesterolIBA 11/2022 - 02/2002
28	Phytosterols (Plant Sterols)IBA 01/2021 - 01/2004
24	LipidsIBA 11/2022 - 07/2005
24	Apolipoproteins E (ApoE)IBA 03/2022 - 01/2003
16	SterolsIBA 02/2022 - 10/2002
15	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2022 - 02/2002
12	ApolipoproteinsIBA 12/2016 - 01/2004
9	LDL CholesterolIBA 08/2020 - 01/2006
9	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2006
8	lathosterolIBA 11/2022 - 01/2004
8	Simvastatin (Zocor)FDA LinkGeneric 01/2021 - 02/2002
8	EstersIBA 01/2020 - 05/2007
8	oxidized low density lipoproteinIBA 01/2019 - 09/2008
8	Lipoproteins (Lipoprotein)IBA 09/2017 - 08/2008
8	Apolipoprotein E4IBA 01/2016 - 01/2003
7	gamma-sitosterol (beta-sitosterol)IBA 12/2021 - 04/2006
7	OxysterolsIBA 01/2021 - 09/2004
7	Bile Acids and Salts (Bile Acids)IBA 01/2021 - 01/2003
7	27-hydroxycholesterolIBA 01/2020 - 01/2004
7	24-hydroxycholesterolIBA 08/2010 - 02/2002
6	campesterolIBA 11/2022 - 09/2009
6	Dietary CholesterolIBA 05/2021 - 08/2008
6	Amyloid (Amyloid Fibrils)IBA 03/2021 - 02/2006
5	Biomarkers (Surrogate Marker)IBA 01/2021 - 02/2006
5	Liver X ReceptorsIBA 01/2021 - 06/2013
5	LDL Receptors (LDL Receptor)IBA 01/2021 - 11/2008
5	Triglycerides (Triacylglycerol)IBA 01/2020 - 02/2013
5	Peptides (Polypeptides)IBA 01/2020 - 01/2003
4	Ezetimibe (Zetia)FDA Link 11/2022 - 10/2002
4	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 02/2013
4	Messenger RNA (mRNA)IBA 01/2021 - 04/2006
4	CytokinesIBA 01/2021 - 11/2015
3	Oxidoreductases (Dehydrogenase)IBA 01/2021 - 06/2004
3	EnzymesIBA 01/2021 - 01/2014
3	HDL CholesterolIBA 01/2020 - 02/2013
3	Insulin (Novolin)FDA Link 01/2020 - 05/2008
3	stigmastanolIBA 10/2018 - 01/2012
3	EndocannabinoidsIBA 01/2018 - 01/2014
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016 - 07/2010
3	Amyloid beta-PeptidesIBA 06/2007 - 01/2003
2	Apolipoproteins B (ApoB)IBA 03/2022 - 11/2014
2	Cholestanol (Coprostanol)IBA 02/2022 - 07/2015
2	polyglutamineIBA 01/2021 - 05/2008
2	Tumor Biomarkers (Tumor Markers)IBA 01/2021 - 01/2011
2	Ataxin-2IBA 01/2021 - 05/2008
2	Cathepsin DIBA 01/2021 - 01/2017
2	Proprotein Convertase 9IBA 11/2020 - 10/2007
2	cholest-5-en-3 beta,7 alpha-diolIBA 01/2020 - 09/2004
2	Transcription Factors (Transcription Factor)IBA 01/2020 - 06/2013
2	LDL Lipoproteins (beta Lipoproteins)IBA 01/2019 - 01/2006
2	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2018 - 07/2010
2	glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA 01/2018 - 01/2016
2	LigandsIBA 01/2018 - 01/2018
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 09/2017 - 01/2012
2	Biological ProductsIBA 12/2016 - 07/2010
2	Hydroxyproline (4 Hydroxyproline)IBA 10/2016 - 08/2015
2	plant stanol esterIBA 02/2016 - 01/2012
2	Interleukin-10 (Interleukin 10)IBA 01/2016 - 01/2012
2	Fatty Acids (Saturated Fatty Acids)IBA 10/2015 - 03/2014
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 11/2014 - 06/2014
2	CollagenIBA 01/2014 - 07/2010
2	DesmosterolIBA 01/2014 - 01/2010

Therapy/Procedure

10	Therapeutics 01/2021 - 09/2006